Xience stents elute which drug?

Xience stents elute which drug?

• A. Everolimus
• B. Sirolimus
• C. Paclitaxel
• D. Zotarolimus

Answer: (A)

Xience stents are everolimus-eluting devices. Everolimus is a rapamycin analog that inhibits the mTOR pathway, reducing smooth muscle cell proliferation after stent placement and thus lowering restenosis risk. This distinguishes Xience from other drug-eluting stents that use sirolimus, zotarolimus, or paclitaxel. Sirolimus is an older mTOR inhibitor, zotarolimus is another mTOR inhibitor used in different stent platforms, and paclitaxel works by a different mechanism (microtubule stabilization). The everolimus-eluting design of Xience has been associated with favorable healing and restenosis outcomes compared with some older drug-eluting platforms.

Xience stents are everolimus-eluting devices. Everolimus is a rapamycin analog that inhibits the mTOR pathway, reducing smooth muscle cell proliferation after stent placement and thus lowering restenosis risk. This distinguishes Xience from other drug-eluting stents that use sirolimus, zotarolimus, or paclitaxel. Sirolimus is an older mTOR inhibitor, zotarolimus is another mTOR inhibitor used in different stent platforms, and paclitaxel works by a different mechanism (microtubule stabilization). The everolimus-eluting design of Xience has been associated with favorable healing and restenosis outcomes compared with some older drug-eluting platforms.